Decomposition of high-frequency electrical conductivity into extracellular and intracellular compartments based on two-compartment model using low-to-high multi-b diffusion MRI
نویسندگان
چکیده
Abstract Background As an object’s electrical passive property, the conductivity is proportional to mobility and concentration of charged carriers that reflect brain micro-structures. The measured multi- b diffusion-weighted imaging (M -DWI) data by controlling degree applied diffusion weights can quantify apparent water molecules within biological tissues. Without any external stimulation, magnetic resonance properties tomography (MREPT) techniques have successfully recovered distribution at a Larmor-frequency. Methods This work provides non-invasive method decompose high-frequency into extracellular medium based on two-compartment model using M -DWI. To separate intra- micro-structures from conductivity, we include higher -values DWI apply random decision forests stably determine micro-structural parameters. Results demonstrate proposed method, conducted phantom human experiments comparing results reconstructed in intra-neurite intra-cell body. verify recover routine protocol sequence MRI scan. Conclusion We extracellular, intra-neurite, soma compartments map, solving electro-magnetic equation with B1 phase signals.
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ژورنال
عنوان ژورنال: Biomedical Engineering Online
سال: 2021
ISSN: ['1475-925X']
DOI: https://doi.org/10.1186/s12938-021-00869-5